Replacing Opioids: Natural Compound Promises Pain Relief Without Addiction
Researchers at Mainz University have discovered a natural compound that could potentially serve as a long-term alternative to opioids and may help alleviate the opioid…
Pharmacology News
Pharmacology is the scientific discipline that studies how drugs interact with biological systems. It involves the discovery, chemical properties, biological effects, and therapeutic uses of drugs, encompassing both the beneficial effects and the adverse effects of these substances. Pharmacologists explore the molecular mechanisms by which drugs act in the body to develop new therapeutic agents and improve the efficacy and safety of existing treatments. This field is crucial for the advancement of medicine, enabling the development of new drugs that can treat a wide range of diseases more effectively. Pharmacology is divided into various branches, including clinical pharmacology, which deals with the effects of drugs in humans, and toxicology, which studies the harmful effects of chemicals on living organisms.
Innovative Light-Controlled Drugs Could Revolutionize Neuropathic Pain Treatment
A team of researchers from the Institute for Bioengineering of Catalonia (IBEC) has developed light-activated derivatives of the anti-epileptic drug carbamazepine to treat neuropathic pain….
“I’ve Never Seen This Before” – Scientists Have Discovered the First Temporary, Universal Taste Blocker
The procedure for taking essential yet bitter medicine looks promising. Many people, particularly children and the elderly, struggle with swallowing pills. Liquid medications often taste…
Navigating the Neurochemical Maze of Antidepressant Withdrawal
Expectations contribute to symptoms following discontinuation of antidepressants. How difficult is it to stop taking antidepressants? If countless Internet posts and multiple scientific studies are…
Breaking Free From Antidepressants: Lancet Psychiatry Study Uncovers the Risks of Discontinuation Symptoms
About 15% of individuals stopping antidepressants face discontinuation symptoms, with severe cases in 3%. This data, from a review of 79 trials, highlights the potential…
Lifesaving Discovery – First Effective Treatment Found for Spitting Cobra Snakebite
Scientists have developed a pioneering treatment for snakebites that effectively prevents the severe tissue damage inflicted by the venom of African spitting cobras. Spitting cobra…
The Dawn of Green Chemistry: Researchers Unveil Tenfold Increase in Reaction Efficiency
Anyone who wants to produce medication, plastics or fertilizer using conventional methods needs heat for chemical reactions – but not so with photochemistry, where light…
When Medications Collide: New Model Identifies Drugs That Shouldn’t Be Taken Together
Using a machine-learning algorithm, researchers can predict interactions that could interfere with a drug’s effectiveness. Any drug that is taken orally must pass through the…
The GPCR Puzzle: New Research Reveals Molecular Origins of Function for a Key Drug Target
Scientists at St. Jude Children’s Research Hospital, collaborating internationally, used data science, pharmacology, and structural details to explore at the atomic level how each amino…
Artificial Intelligence Paves Way for Synthesizing New Medicines
Researchers have created an artificial intelligence system capable of predicting where a drug molecule can be chemically altered. A collaborative team from LMU, ETH Zurich,…
AI-Powered Drug Design: A Leap in Pharmaceutical Innovation
The ‘reactome’, an AI-powered platform developed by Cambridge and Pfizer, revolutionizes drug design by accurately predicting chemical reactions, streamlining the pharmaceutical development process. Researchers have…
Double Your Odds of Quitting Smoking With Cytisine – If You Can Find It!
Cytisine, a generic smoking cessation aid, has been shown to double the success rate of quitting smoking compared to a placebo. Despite its safety and…
Answering a 40-Year-Old Question – Scientists Reveal Structures of Neurotransmitter Transporter
Neurons communicate through chemical signals known as neurotransmitters. Researchers at St. Jude Children’s Research Hospital, leveraging their expertise in structural biology, have successfully elucidated the…
Antidepressants vs. Running: What Works Best to Beat Depression
First trial to directly compare effects of treatments on mental and physical health shows clear benefits of exercise, and slight physical worsening with antidepressants. But…
Key Weakness of COVID-19 Discovered
A research study found that without key proteins, the virus cannot infect people. Recent research from UC Riverside has identified COVID’s Achilles heel — its…
Outsmarting Cystinosis: AI-Led Discovery Brings Hope for Patients With Lyosomal Storage Disease
Artificial intelligence is becoming increasingly important in drug discovery. Advances in the use of Big Data, learning algorithms and powerful computers have now enabled researchers…
Tackling Both Stress and Depression – A New Potential Depression Treatment With Minimal Side Effects
Researchers have developed a potential depression treatment that demonstrates both stress-relieving and anti-depressant effects with minimal side effects. Millions of individuals globally grapple with depression…
Researchers Point to the Source of Serious Side Effects in Widely-Used Painkiller
According to recent research, the safety issues surrounding the commonly used pain reliever, diclofenac, may be linked to a poorly understood drug-metabolizing enzyme. The expression…