Structural Biology News

Structural biology is a subfield of molecular biology, biochemistry, and biophysics concerned with the molecular structure of biological macromolecules like proteins, nucleic acids, and their complexes. It aims to provide a detailed understanding of the molecular architecture of these macromolecules and how alterations in their structures affect their function. Techniques such as X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and cryo-electron microscopy (cryo-EM) are commonly used to determine the positions of atoms within a molecule in three-dimensional space. Insights gained from structural biology are crucial for elucidating the mechanisms of biological processes and for designing drugs that can interact with proteins and other targets at the molecular level. This field has contributed significantly to the development of new therapeutics, understanding disease mechanisms, and the design of novel enzymes for industrial applications.