Ecklonia cava, a type of brown algae seaweed, has demonstrated potential in protecting against neurodegenerative diseases.
Parkinson’s disease is a neurodegenerative disorder characterized by the degeneration of dopamine-producing neurons, which are crucial for motor control and cognitive functions. As the worldwide population ages, the prevalence of Parkinson’s disease is quickly rising. This condition results from neuronal damage that occurs due to an overproduction of reactive oxygen species.
Suppression of reactive oxygen species generation is essential because it is fatal to dopaminergic neurons that manage dopamine neurotransmitters. Currently, only symptomatic treatment is available, so the development of treatment regimens and prevention methods is necessary.
Fortunately, Associate Professor Akiko Kojima-Yuasa of Osaka Metropolitan University’s Graduate School of Human Life and Ecology led a research group that has verified the physiological effect of Ecklonia cava polyphenols, seaweed antioxidants, on the prevention of Parkinson’s disease.
Study Findings and Potential Implications
In this study, two types of motor function tests were conducted using Parkinson’s disease model mice that were orally fed the antioxidants daily for one week and then administered rotenone. Results showed that motor function, which was decreased by rotenone, was restored. There was also improvement in intestinal motor function and the colon mucosa structure, a special tissue that covers the colon.
Further, cellular experiments using Parkinson’s disease model cells verified the biochemical interaction of the preventive effect of Ecklonia cava. Validation results showed that the antioxidants activate the AMPK enzyme (adenosine monophosphate-activated protein kinase), an intracellular energy sensor, and inhibit the production of reactive oxygen species that cause neuronal cell death.
“This study suggests that Ecklonia cava antioxidants may reduce neuronal damage by AMPK activation and inhibiting intracellular reactive oxygen species production,” stated Professor Kojima-Yuasa. “It is hoped that Ecklonia cava will be an effective ingredient in the prevention of Parkinson’s disease.”
Reference: “Ecklonia cava Polyphenols Have a Preventive Effect on Parkinson’s Disease through the Activation of the Nrf2-ARE Pathway” by Yuri Yasuda, Tamaki Tokumatsu, Chiharu Ueda, Manami Sakai, Yutaro Sasaki, Toshio Norikura, Isao Matsui-Yuasa and Akiko Kojima-Yuasa, 27 June 2024, Nutrients.
DOI: 10.3390/nu16132076
The study was funded by the Japan Society for the Promotion of Science.
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10 Comments
Keep up the good work
The reference that is appended to this posting has nothing to do with the information that is in the post.
Thank you for your note, we were provided the incorrect DOI. The article has been fixed.
Best,
Colin @ SciTechDaily.com
Keep up the good work which cannot be overstated
Pardon my Interruption. After Accidents, War and Conflicts. Many other things are killing Human being. Like Sickness and Deasesses. No body Die in one day we all Die gradually. It take time to Die, A long time. In Tennis they called something on Force Error. This means the Sickness, Deasesses and Pain Human being are having is there own making. Before Human being, Animals have lived on this Planet / Earth before Human beings and Animals live for
Millions of years if not Billion of years. During that time Animals don’t have Doctors or Scientists among them. And Animals survived. If not the Asteroid that hit the planet Dinosaur will still be around. In so called Animals Planet, Only Human being take Bath or Shower everyday, only Human Washes there Mouths everyday, only Human beings washes there, Plates, Cups, Spones, all there Kitchen utensils everyday. After food. Only Human being washes there Clothes or Clothing may be every weekend and they were doing all this with Soaps / Chemical = Poison. When human wakes up in the Morning first thing they do is washes there Mouths with Toothbrush and Toothpaste. The toothpaste is a Soaps or called it chemicals / Poison and they were using this chemicals to washes there Mouths, Skin / Body every every day. If you ask the Scientists or all this Soaps / Chemicals / Poison Manufacturers if there products are save, they are going to say they are working to make it better. In products label there is waning there that said do not eat or drink. That means you can not eat or drink. That is dangerous and Human being are using that chemicals to brush there Mouths and another chemicals to washes there body and Skin. If you go to Gym, do exercise or do any had labour you will sweat, there are small small hole in your body where you sweat from, so when you shower or take Bath with Soaps or without soap or chemicals. Your skin take water in through this small small hole in to your body with that chemicals and soap. The toothpaste, Soaps, Chemicals / Poison you are using every day is damaging your body and your DNA. Because your body and your DNA has been damaging for so long your body is acceptable to Sickness and Deasesses. Like Skin Cancers, Long Cancers, lost of hair, Blood Sugar, high blood pressure, Diabetics, Trout cancer, Pain, cronies pain, sirious pain and many other Deasesses. Anything you can not eat or drink should not touch your body as well. If we as a Human can stop or reduce the using of all this Soaps, Cchemicals / Poison / toothpaste we will have chances of Surviving. This chemicals has done so much damage to our body, to our Skin, to our DNA. I hope if we can stop or reduce the using of all this Soaps or chemicals our life will be better. The pain people are having we stop or reduce. The Sickness and Deasesses will go away or reduce. Some washes there Mouths with Toothbrush and Toothpaste more than 3 times a day, that’s alone is a sickness. That’s Dum. Thanks. To be continued. M. Luke.
Human being and Animals are perfect Specimen. Right species for this Planet. But the rate human beings are killing themselves is Alarming. They are killing themselves through War and Conflicts. Am coming back to that later Or killing themselves through what Tennis called on Force Error. They are killing themselves faster than they can be replaced. Now they have Graduated from Bone and Arrow, from Swords and Cutlases, from Spears and Knives, To Guns and Bullets, to Bombs and Rockets. To Nucleus and Chemicals Bombs. I know every body know what rights from wrong. Thanks. To be continued. M. Luke.
Human being should not be blaming God for there unforced Error. For all there Problems, because many of there Problems are man made. Apart from War and Conflicts the rest are Man made. Like consuming or Eating Soaps and Chemicals = Poison for every day, for weeks, for Mouths and for years, which is cursing them so many Sickness and Deasesses like Cancer and many other Deasesses. The Water we have is going to last for while. The Water is for drinking purposes and to make Food. The rest is Luxuries. Your Health is important than your sinning Teeth and Smooth Skin. Now if you must washes your mouth and your skin, you must washes them with only water. For example. Put water into your mouth for about 2 to 5 minutes, use your Tongue to move the water up and down. After food. If you are still filing something in your teeth then use toothpick to remove it. Washes your mouth every day is sickness, is Dum, is Stupid. About your body or Skin, you don’t need Soaps or chemicals to washes your body or your mouth. You can washes your body with only water and not every day, may be once or twice a week. With soap maybe once a month. Or few times a year. Your mouth is and teeth is not smelling so you don’t need Soaps or chemicals every day to washes them. Your body and your skin is not smelling or Rotten as well. Stay away from what can kills you. Please Stay away from Soaps, Chemicals = Poison. Washes your Clothing with only water. If they are too dirty trow it away. Avoid using soap or chemicals as much as possible. To repair your DNA is going to take a while, more than 50 percent of your DNA has been damage, So what you can do for now is praying that is not to late. Stay away from eating Soaps and Chemicals. Thanks. To be continued. M. Luke.
If you check the actual study, it has this:
“Competing interests — MH received research funding and speaker honoraria from AbbVie and Nippon Shinyaku Co. Ltd. HN received speaker honoraria from AbbVie and Nippon Shinyaku Co. Ltd. M Nishimoto, and HO received speaker honoraria from Nippon Shinyaku Co. Ltd. YN, and TT received funding from AbbVie. The remaining authors declare no competing interests.” This means there is a bias and conflict of interest in this study.
It is also interesting that they call this a prevention of Parkinson’s, but it is a treatment, not a prevention. Parkinson’s is not caused by a lack of seaweed.
It is unfortunate that this study tortures animals. “In this study, two types of motor function tests were conducted using Parkinson’s disease model mice that were orally fed the antioxidants daily for one week and then administered rotenone. Results showed that motor function, which was decreased by rotenone, was restored. There was also improvement in intestinal motor function and the colon mucosa structure, a special tissue that covers the colon.” That means these animals suffered at the hands of these people. All to sell seaweed pills.
Could you please address the proper reference? The one that is posted is not the right one.
Thank you for your note, we were provided the incorrect DOI. The article has been fixed.
Best,
Colin @ SciTechDaily.com