Stopping Acute Myeloid Leukemia Stem Cells in Their Tracks
The discovery of two growth regulators involved in acute myeloid leukemia relapse offers hope for targeted therapies to prevent recurrence, emphasizing the need for further…
Leukemia is a type of cancer that primarily affects the blood and bone marrow, characterized by the rapid production of abnormal white blood cells. These defective cells do not function properly and can crowd out healthy blood cells, impairing the body’s ability to fight infections, carry oxygen, and control bleeding. Leukemia is categorized based on the speed of progression—acute, which develops quickly, and chronic, which progresses more slowly—and the type of blood cells affected, mainly lymphocytes or myeloid cells. Common symptoms include fatigue, frequent infections, bleeding or bruising easily, and weight loss. The causes of leukemia are not completely understood but are believed to involve a combination of genetic and environmental factors. Treatment varies depending on the type of leukemia and may include chemotherapy, radiation therapy, targeted therapy, and bone marrow transplant. Advances in medical research have significantly improved the prognosis and treatment options for many patients with leukemia.
The discovery of two growth regulators involved in acute myeloid leukemia relapse offers hope for targeted therapies to prevent recurrence, emphasizing the need for further…
Personalized therapy enhances survival rates for patients with CLL leukemia. A phase III trial conducted by the University of Leeds discovered that personalized treatment for…
New research reveals that CRISPR-Cas9 gene editing can unintentionally lead cancer cells to remove crucial genes, impacting cancer research and treatment strategies. A new study…
Researchers report that enhancing the accuracy of detecting a particular molecular marker in leukemic cells can significantly improve the assessment of measurable residual disease. This…
Findings should inform rules on workplace protection from low-dose radiation, say researchers. Prolonged exposure to low-dose ionizing radiation is associated with a higher risk of…
Researchers from UCL, Great Ormond Street Hospital, and the Wellcome Sanger Institute have unveiled findings that shed light on why certain children experience extended remission…
Scientists at the University of Tsukuba have discovered an unexpected connection between an enzyme known as ELOVL6, important in lipid metabolism, and the proliferation of…
An MIT research team has made a breakthrough in improving the effectiveness of engineered T cells, or chimeric antigen receptor (CAR) T cells, in treating…
Future clinical trials will be conducted to investigate whether the combination of chloroquine and venetoclax can prevent disease recurrence. Although new drugs have been developed…
A diet rich in vitamin A or its derivatives may aid in reducing the likelihood of developing painful pancreatic inflammation in children and young adults…
A protein degrader shows potential in targeting STAT5, a protein involved in leukemia and other forms of cancer. For decades, researchers have been interested in…
Scientists at St. Jude Children’s Research Hospital are reporting the most comprehensive study to date describing the variations in drug response across different genetic subtypes…
Researchers discover a new class of drugs that provide leukemia patients with a safer, more targeted form of therapy. Chemotherapy isn’t fun. It’s no secret…
A mechanism is discovered that explains how cancer cells transform into normal, harmless ones. A recent study explains how changing the chemical modifications, or so-called epigenetics,…
Scientists found they could optimize drug concentrations to simultaneously target two molecular signaling pathways responsible for cancer growth by using the lymphatic system as a…
New research changes a natural substance such that it may be used as a potential treatment for acute myeloid leukemia. Natural substances often have therapeutic…
Everybody possesses a tiny number of unusual thymocyte cells, and in some cases, these cells develop into leukemia. Researchers have discovered that T-cell acute lymphoblastic…
New study highlights potential of mitochondria-targeted chemotherapies. Scientists have discovered promising new drugs that work in concert with other drugs to deliver a deadly one-two…