Unlocking Secrets to Extend Fertility With Long-Lived Proteins
Max Planck researchers have discovered that extremely long-lived proteins in the ovary may keep mammalian egg cells healthy and preserve fertility for a long time….
Mitochondria News
Mitochondria are organelles known as the powerhouses of the cell because they generate most of the cell’s supply of adenosine triphosphate (ATP), used as a source of chemical energy. They are found in the cells of nearly all eukaryotic organisms, from fungi to plants to animals. Mitochondria are unique among organelles because they have their own independent DNA, which supports the theory that they originated from free-living prokaryotes that entered into a symbiotic relationship with primitive eukaryotic cells. This process is known as endosymbiosis. Mitochondria are involved in several other critical cellular processes, including signaling, cellular differentiation, cell death, as well as the control of the cell cycle and cell growth. Moreover, mitochondria play a crucial role in the regulation of the cell’s metabolic control, and their dysfunction is linked to a range of diseases, particularly those affecting tissues with high energy demands like the heart and brain, as well as aging.
Unlocking the Secrets of Aging: Chinese Researchers Discover Potential Key to Alzheimer’s Disease
A groundbreaking study conducted by Prof. Qiang Liu’s team at the University of Science and Technology of China (USTC), and published in the journal Cell…
A New Way To Treat Obesity? Scientists Discover Surprising Effects of New Drug
Researchers at Karolinska Institute have potentially discovered a novel method to combat obesity and associated conditions by focusing on the mitochondria, the powerhouses of the…
Scientists Identify Key Cause of Female Infertility
Approximately 48 million couples globally face infertility challenges, which can arise from multiple factors. In mammals, such as humans, the ovaries are responsible for egg…
Scientists Uncover the Hidden Role of Mitochondria in Dietary Fat Processing
Maintaining balanced lipid levels is essential for good health. Consuming too much fatty food can lead to metabolic disorders like obesity and atherosclerosis, but fats…
Cancer Immunotherapy Treatment 2.5x More Effective With Mitochondrial DNA Mutations
A groundbreaking study shows that mitochondrial DNA mutations are key indicators of a patient’s likelihood to respond to immunotherapy, revolutionizing cancer treatment approaches. Cancer Research…
Deleting a Key Gene Shields Against Excess Weight Gain
UC San Diego Study reveals key mechanism behind obesity-related metabolic dysfunction. The number of people with obesity has nearly tripled since 1975, resulting in a…
Scientists Have Discovered a Previously Unknown Protein Capable of Keeping Human Cells Healthy
Researchers have discovered a previously unidentified protein with antioxidant properties produced by Coxiella burnetii, a Gram-negative intracellular bacterium. This breakthrough suggests potential new treatments for…
Aging’s Antidote? The Crucial Role of HKDC1 in Keeping Cells Youthful
Researchers from Osaka University have identified a protein called HKDC1 that’s crucial to maintaining two subcellular structures, mitochondria and lysosomes, thereby preventing cellular senescence. Just…
Long-Standing Mystery Solved: New Findings Rewrite Understanding Into Parkinson’s Disease Pathway
Researchers from Melbourne’s Walter and Eliza Hall Institute (WEHI) have unraveled a long-standing mystery surrounding a protein’s role in clearing the body of damaged mitochondria….
Mitochondrial Meltdown: Researchers Unveil COVID-19’s Hidden Attack on Vital Organs
Mitochondrial function in the lungs showed recovery, but this was not the case for the heart and other organs. This persistent damage could provide a…
Calcium Uptake: New Discovery Could Slow Aging and Prevent Age-Related Diseases
University of Virginia School of Medicine researchers have discovered a key driver of chronic inflammation that accelerates aging. That finding could let us slow the clock to live longer,…
Gene Mutation Discovery Reveals New Therapeutic Target for Parkinson’s Disease
Restoring contacts between mitochondria and lysosomes improves neuronal function. Contacts between lysosomes and mitochondria are broken due to Parkinson’s mutation Lysosomes cannot ‘feed’ mitochondria with…
Death to Blood Cancer Cells: New Drug Combination Could Revive the Power of Leading Treatment
Future clinical trials will be conducted to investigate whether the combination of chloroquine and venetoclax can prevent disease recurrence. Although new drugs have been developed…
Powerhouse Puzzle Solved: How a Massive Supercomplex in Mitochondria Shapes Cellular Respiration
A new study has revealed how respiratory supercomplexes, consisting of four associated respiratory complexes, shape the mitochondrial membrane in the single-cell eukaryote, Tetrahymena thermophila. The…
“Surprising” Findings – Scientists Identify Complete Respiratory Supercomplex
For the first time, researchers have found a complex of proteins that contains the four central components for optimized energy production. This discovery is of…
New Research Reveals How a Metabolite Causes Inflammation and Disease
A groundbreaking study has uncovered a link between a mitochondrial metabolite and the triggering of an inflammatory response. As essential components of our cells, mitochondria…
“Completely Unknown Until Now” – New Intracellular Smoke Detector Discovered
A research project carried out by the University of Bonn holds promise for the development of treatments for skin and gut disorders in the medium…