T-cells, or T lymphocytes, are a type of white blood cell that play a central role in the immune response and are essential for adaptive immunity. They are produced in the bone marrow and mature in the thymus, which is where they derive their name. T-cells are distinguished by their T-cell receptors that allow them to recognize and bind to specific antigens presented by other cells. There are several types of T-cells, including helper T-cells, which assist other immune cells; cytotoxic T-cells, which kill virus-infected cells and cancer cells; and regulatory T-cells, which help maintain immune tolerance and prevent autoimmune diseases. Their ability to target specific antigens makes T-cells crucial in the body’s defense against pathogens, in tumor suppression, and in the overall regulation of the immune system.
Cambridge researchers have discovered that regulatory T cells traverse the body to repair tissue, opening avenues for targeted treatments in various diseases. Researchers at the…
Researchers at St. Jude Children’s Research Hospital and the University of Minnesota have discovered that the aging of T-cells is not constrained by the age…
Researchers from the University of Houston identified CD8-fit T cells with high motility and serial killing abilities, potentially enhancing T-cell cancer therapies. The study used…
FOXO1 is required for T cell memory and is linked to longer-lasting clinical outcomes in CAR T cell therapy. CAR T cell therapy has transformed…
A CRISPR-based platform has discovered numerous genes with the potential to enhance T-cell therapies for cancer treatment. Researchers at Duke University have advanced CRISPR technologies…
A cross-disciplinary group of scientists at the Otto-von-Guericke University in Magdeburg has unveiled a new understanding of how inflammatory mediators of pathogen defense can remotely…
Researchers from Kobe University have identified an entirely new and unexpected mechanism through which the immune system eliminates cells lacking molecules that identify them as…
New recent research from Yale has discovered a method to control the self-destructive tendencies of certain killer T cells utilized in cancer therapy. CAR T-cell…
MitoQ, a publicly accessible dietary supplement that acts as a mitochondrial antioxidant, was discovered through a mouse study to counteract the harmful impacts that HIV…
During the COVID-19 pandemic, medical professionals and researchers observed that children and teenagers who contracted the virus exhibited milder symptoms compared to adults. This phenomenon…
Artificial intelligence platform has the ability to efficiently design T-cell-based vaccines that offer broad protection. The platform could also be used to develop seasonal flu…
According to new research, children exhibit a robust initial immune response to the coronavirus, however, they are unable to transfer this response to long-lasting memory…
Targeting iron metabolism in immune system cells could be a potential new approach for treating systemic lupus erythematosus (SLE), the most prevalent form of the…
A new immunotherapy releases cancer-killing cytokines only within the tumor. Researchers at the University of California San Francisco (UCSF) have developed a new T cell-based…
Everybody possesses a tiny number of unusual thymocyte cells, and in some cases, these cells develop into leukemia. Researchers have discovered that T-cell acute lymphoblastic…
Researchers discover a new mechanism for activating cancer-killing T cells Researchers have made significant progress in the discovery and administration of cancer immunotherapies, which employ…
Processes in the human body transform harmless immune cells into ruthless killers According to a recent study, the human body has the capability to change…
UCLA researchers use stem cells to engineer cells that attack human tumors in mice. They’ve been called the “special forces” of the immune system: invariant…