Biology News RSS feed for this section

New Method for Detecting Unwanted DNA Breaks in Human Cells

December 18, 2014

0 Comments

New Method for Detecting Unwanted DNA Breaks

Researchers at the Harvard Medical School have developed a new method for detecting unwanted DNA breaks across the entire genome of human cells induced by the popular gene-editing tools called CRISPR-Cas RNA-guided nucleases. Members of the same team that first described these off-target effects in human cells describe their new platform, called GUIDE-seq (Genome-wide Unbiased […]

Continue reading...

Scientists Create the First 3D Maps of Entire Folded Genomes

December 15, 2014

0 Comments

The First High-Resolution 3D Maps of Entire Folded Genomes

A team of researchers has created the first 3D maps of entire folded genomes, identifying approximately 10,000 folding loops in the human genome. In a triumph for cell biology, researchers have assembled the first high-resolution, 3-D maps of entire folded genomes and found a structural basis for gene regulation, a kind of “genomic origami” that […]

Continue reading...

Gene-Editing System Allows Rapid, Large-Scale Studies of Gene Function

December 11, 2014

1 Comment

Researchers Develop a New Technique to Study Gene Function

Using a gene-editing system that was originally developed to delete specific genes, researchers from MIT developed a new technique to reliably turn on any gene of their choosing in living cells. This new application for the CRISPR/Cas9 gene-editing system should allow scientists to more easily determine the function of individual genes, according to Feng Zhang, […]

Continue reading...

A Pill to Shed Fat? Researchers Turn White Fat Cells Into Brown Fat Cells

December 10, 2014

0 Comments

Researchers Turn White Fat Cells into Brown Fat Cells

Scientists from Harvard have created a system using human stem cells to screen for compounds that have the potential to turn white fat cells into brown fat cells. Harvard Stem Cell Institute (HSCI) researchers have taken what they describe as “the first step toward a pill that can replace the treadmill” for the control of […]

Continue reading...

New Research Details Why Typhoid Toxin Targets Only Humans

December 8, 2014

0 Comments

Study Reveals Why Typhoid Toxin Targets Only Humans

Scientists at Yale and UC San Diego have discovered why typhoid toxin targets only humans, revealing a single oxygen atom is the cause. The bacterium Salmonella Typhi causes typhoid fever in humans, but leaves other mammals unaffected. Researchers at University of California, San Diego and Yale University Schools of Medicine now offer one explanation — […]

Continue reading...

Research Reveals New Strategy to Control Cellular Identity and Fate

December 5, 2014

0 Comments

A New Strategy to Control Cellular Identity and Fate

Newly published research suggests a new strategy to control cellular identity and fate, revealing that depleting or knocking out a chemical tag on RNA keeps embryonic stem cells in suspended animation. A team of scientists that included researchers from UCLA has discovered a novel mechanism of RNA regulation in embryonic stem cells. The findings are […]

Continue reading...

Biologists Decode the 3D Structure of the Calcium Channel

December 2, 2014

1 Comment

Scientists Decode the 3D Structure of the Calcium Channel

Scientists at the Max Planck Institute of Molecular Physiology in Dortmund have decoded the three-dimensional structure of the calcium channel with unprecedented accuracy. Whenever muscles contract, so-called ryanodine receptors come into play. Calcium ions, which are ultimately responsible for the contraction of muscle cells, are released from storage organs and flow through these ion channels. […]

Continue reading...

White Matter Changes Allow Older People to Learn New Visual Tasks

November 21, 2014

1 Comment

White Matter Changes Allow Older Brains to Learn

New research from Brown University shows that older people can learn a visual task just as well as younger ones, revealing that a significant change in the white matter of the brain takes place when the older subjects learn. Providence, Rhode Island (Brown University) — A widely presumed problem of aging is that the brain […]

Continue reading...

Researchers Pinpoint Common Culprits for Autoimmunity in Plants

November 20, 2014

1 Comment

Overzealous Plant Immune System Can Be Deadly

Scientists from the Max Planck Institute for Developmental Biology have now pinpointed the most common culprits for autoimmunity in plants. Plants are under permanent attack by a multitude of pathogens. To win the battle against fungi, bacteria, viruses and other pathogens, they have developed a complex and effective immune system. And just as in humans, […]

Continue reading...

Discovery Hints at New Strategy for Fighting HIV

November 19, 2014

0 Comments

New Strategy for Fighting HIV

Researchers from Yale University have discovered an immune system reaction that may open a new avenue in the fight against HIV. The discovery of the innate immunity system’s role in mobilizing the body’s defenses against invading microorganisms has been long studied at Yale. Now in the November 17 issue of the journal Nature Immunology, Yale […]

Continue reading...

Engineered Bacteria Store Memories of Chemical Exposure

November 17, 2014

0 Comments

Engineered Bacteria Can Store Memories of Chemical Exposure

New research from MIT reveals that engineered E. coli can store long-term memories of chemical exposure and other events in their DNA. MIT engineers have transformed the genome of the bacterium E. coli into a long-term storage device for memory. They envision that this stable, erasable, and easy-to-retrieve memory will be well suited for applications […]

Continue reading...

The Rapid-Fire Evolution of Green Anoles

November 13, 2014

0 Comments

Native Lizards Show Rapid Fire Evolution

A newly published study from Harvard University found that in just 20 generations in 15 years green anoles evolved larger toe pads equipped with more sticky scales to allow for better climbing. Though it’s often portrayed as a process that takes place over thousands of years, under the right circumstances the evolution of enhanced traits […]

Continue reading...

New Algorithm Predicts the Evolution of Viruses

November 12, 2014

0 Comments

Algorithm Can Predict the Evolution of Viruses

Using the branches of a genealogical tree as reference, a team of scientists has developed an algorithm that can predict the evolution of asexual organisms such as viruses or cancer cells. For a long time, prognoses forecasting the evolutionary future of organisms were considered mere speculation. Together with researchers from Cambridge and Santa Barbara, USA, […]

Continue reading...

Type 2 Diabetes and Cardiovascular Disease Share Eight Molecular Pathways

November 4, 2014

0 Comments

Type 2 Diabetes and Cardiovascular Disease May Be Related

In a newly published study, researchers uncover several potential ways that type 2 diabetes and cardiovascular disease may be related at the level of genes, proteins, and fundamental physiology in women. Providence, Rhode Island (Brown University) — Type 2 diabetes (T2D) and cardiovascular disease (CVD) appear to have a lot in common. They share risk […]

Continue reading...

Molecular Map Pinpoints Genetic Variants of Autoimmune Diseases

October 30, 2014

0 Comments

New Molecular Map Reveals Genetic Origins of Autoimmune Diseases

Researchers have developed a molecular map that pinpoints genetic variants that play a role in 21 different autoimmune diseases, providing new insight into the cause of multiple sclerosis and other autoimmune diseases. Researchers at Yale, the University of California-San Francisco (UCSF), and the Broad Institute of MIT and Harvard developed a sophisticated mathematical model and […]

Continue reading...